It's not merely students of Classical Greek that will regard these letters as familiar, but astronomers. The first 26 stars in a constellation are assigned Greek letters, followed by the genitive form of the containing constellation, in order of magnitude (with a few historical errors persisting).
For example, in the constellation Orion, the star Betelgeuse is Alpha Orionis, and Rigel is Beta Orionis. When these were named for their status in the constellation in the Bayer Catalogue, Betelgeuse was visibly brighter than Rigel, but of course, Betelgeuse has since been found to be a variable star whose magnitude fluctuates over long periods of time.
Among the notable 'omicrons' are:
Omicron Cephei - close binary star system
Omicron Persei - triple star system
Omicron Ursae Majoris - star with an exoplanet known to be orbiting it
Omicron1 Eridani - variable star of the Delta Scuti class, with rapid rotation and large equatorial bulge
Omicron1 Canis Majoris - distant red supergiant and irregular variable star
Incidentally, returning to Classical Greek for a moment, omicron and omega, the two letters for o-type vowel sounds in Greek words, are named appropriately for the type of vowel sound - omicron (o-micron) is for short (small) o-vowel sounds, and omega (o-mega) for long (large) o-vowel sounds.
For those who love minutiae of this sort, these two vowels can also be found written with what is known as the 'iota subscript' directly underneath. The use of an iota subscript to denote a following iota has had numerous hilarious consequences, courtesy of the fact that an iota subscript can be mistaken for a dirt mark on a papyrus, resulting in translation controversies.